DEXTRAN SULFATESMID : 4294
INCI NAME : SODIUM DEXTRAN SULFATE
| DEXTRAN SULFATES MID : 4294 INCI NAME : SODIUM DEXTRAN SULFATE |
| Name | Brand name | Generic name | Molecular weight of Dextran | Purpose |
|---|---|---|---|---|
| DS | DS S18 | Dextran Sulfate Sodium Sulfur 18 | ca. 1,600 | Antilipotropic drug |
| DS | DS S5 | Dextran Sulfate Sodium Sulfer 5 | ca. 1,600 | Antilipotropic drug |
| DS | DS 500 | Dextran Sulfate Sodium | ca. 500,000 | Diagnostics (cholesterol assay) |
| DS | DST-H | Dextran Sulfate Sodium | ca. 1,600 | Diagnostics (cholesterol assay) |
| DS | DSV-H | Dextran Sulfate Sodium | ca. 500,000 | Cosmetic |
| DS | DSH | Dextran Sulfate Sodium | ca. 1,600 | Medical materials |
| DS S5 | ||
| Test items | The Japanese Pharmacopoeia (15) | |
|---|---|---|
| Description | White to light yellowish white powder, odorless, saline taste | |
| Freely soluble in water and practically insoluble in ethanol and in ether | ||
| Hygroscopic | ||
| Identification | Toluidine blue | Positive |
| Anthrone | Positive | |
| Sodium salt | Positive | |
| Optical rotation | [ ]D: +135.0 - +155.0° (20ºC, 1.5 g, water, 25 mL, 100 mm) |
|
| pH | 5.5 - 7.5 (1.0 g/20 mL) | |
| Purity | Clarity of solution | Clear (2.5 g/50 ml), Absorbance : Not more than 0.090 (at 420 nm) |
| Chloride | Not more than 0.106 % | |
| Sulfate | Not more than 0.240 % | |
| Heavy metals | Not more than 20 ppm | |
| Arsenic | Not more than 2 ppm | |
| Sulfur content | 3.0% - 6.0% | |
| Loss on drying | Not more than 10.0 % | |
| Intrinsic viscosity | 0.030 - 0.040 dL/g | |
| DS S18 | |||
| Test items | The Japanese Pharmacopoeia (15) | Japanese Standards of Quasi-drug Ingredients (JSQI) | |
|---|---|---|---|
| Description | White to light yellowish white powder, odorless, saline taste | White to light yellowish white powder, odorless | |
| Freely soluble in water and practically insoluble in ethanol and in ether | --- | ||
| Hygroscopic | --- | ||
| Identification | Toluidine blue | Positive | Positive |
| Anthrone | Positive | Positive | |
| Sodium salt | Positive | Positive | |
| IR absorption spectrum | --- | Specific absorption is observed | |
| Optical rotation | []D: +90.0 - +110.0° (20ºC, 1.5 g, water, 25 mL, 100 mm) |
[]D: +85 - +115 ° (20ºC, 1.5 g, water, 25 mL, 100 mm) |
|
| pH | 5.5 - 7.5 (1.0 g/20 mL) | 5.0 - 7.5 (1.0  20) |
|
| Purity | Chloride | Not more than 0.106 % | Not more than 0.36 % |
| Sulfate | Not more than 0.480 % | Not more than 0.48 % | |
| Heavy metals | Not more than 20 ppm | Not more than 20 ppm | |
| Arsenic | Not more than 2 ppm | Not more than 2 ppm | |
| Clarity of solution | --- | Colorless to light yellow, clear | |
| Sulfur content | 15.0 % - 20.0 % | 15.0 % - 20.0 % | |
| Loss on drying | Not more than 10.0 % | Not more than 10.0 % | |
| Intrinsic viscosity | 0.020 - 0.032 dL/g | --- | |